Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | PTPRB | P23467 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28650267 | 1.00 | SSTR5 (0.41) | SSTR5KDM4COPRL1PTGDR2HSD11B1 | |
| SCHEMBL30065779 | 0.87 | TP53 (0.38) | SSTR5OPRL1P2RX7RBP4 | |
| SCHEMBL28668984 | 0.87 | TP53 (0.38) | SSTR5OPRL1P2RX7RBP4 | |
| SCHEMBL22203189 | 0.81 | NOTUM (0.41) | KDM4CP2RX7 | |
| SCHEMBL28658960 | 0.80 | SCN8A (0.49) | — | |
| SCHEMBL30065550 | 0.80 | SCN8A (0.49) | — | |
| SCHEMBL30065594 | 0.77 | SORT1 (0.45) | — | |
| SCHEMBL28662755 | 0.70 | ALDH1A1 (0.39) | P2RX7 | |
| SCHEMBL22203190 | 0.70 | ALDH1A1 (0.41) | P2RX7 | |
| SCHEMBL28134554 | 0.70 | PTGDR2 (0.42) | KDM4COPRL1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996774-B | 2-oxo-1,2-dihydropyridine derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2022-11-22 | — | — | CN | disclosed |