Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | RBP4 | P02753 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28668984 | 1.00 | TP53 (0.38) | TP53MAPTOPRL1NR3C2CFTR | |
| SCHEMBL30065551 | 0.87 | SSTR5 (0.41) | OPRL1RBP4P2RX7SSTR5 | |
| SCHEMBL28650267 | 0.87 | SSTR5 (0.41) | OPRL1RBP4P2RX7SSTR5 | |
| SCHEMBL28662755 | 0.85 | ALDH1A1 (0.39) | TP53MAPTNR3C2CFTRP2RX7 | |
| SCHEMBL30065540 | 0.84 | ALDH1A1 (0.41) | TP53MAPTNR3C2CFTRP2RX7 | |
| SCHEMBL22203190 | 0.84 | ALDH1A1 (0.41) | TP53MAPTNR3C2CFTRP2RX7 | |
| SCHEMBL28655627 | 0.83 | PLA2G2A (0.45) | MAPTNR3C2P2RX7ALDH1A1LMNA | |
| SCHEMBL28669416 | 0.81 | SORT1 (0.45) | — | |
| SCHEMBL30065594 | 0.81 | SORT1 (0.45) | — | |
| SCHEMBL28658960 | 0.78 | SCN8A (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996774-B | 2-oxo-1,2-dihydropyridine derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2022-11-22 | — | — | CN | disclosed |