Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 1/20 | 0.55 |
| ▸ | LSS | P48449 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30064686 | 0.91 | KDM4E (0.54) | GPR183LSSPTGS2TP53POLB | |
| SCHEMBL30064678 | 0.88 | TP53 (0.59) | GPR183LSSTP53POLBLMNA | |
| SCHEMBL30064696 | 0.81 | KDM4E (0.70) | LMNATSHR | |
| SCHEMBL5060872 | 0.78 | CCR1 (0.62) | POLBLMNATSHR | |
| SCHEMBL30064685 | 0.78 | SIGMAR1 (0.56) | POLBLMNATSHR | |
| SCHEMBL30065423 | 0.77 | LMNA (0.60) | POLBLMNA | |
| SCHEMBL2931705 | 0.77 | AKR1C3 (0.65) | GPR183LSSTP53POLBAKR1C3 | |
| SCHEMBL30064781 | 0.76 | — | — | |
| SCHEMBL22972976 | 0.74 | WNK1 (0.62) | GPR183LSSPTGS2TP53POLB | |
| SCHEMBL29719297 | 0.74 | WNK1 (0.62) | GPR183LSSPTGS2TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110615774-B | Benzyl piperazine compound with anti-inflammatory activity, preparation method and medical application | 安徽中医药大学 | 2022-11-11 | — | — | CN | disclosed |