Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | KDM5A | P29375 | 4/20 | 0.45 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.45 |
| ▸ | JMJD1C | Q15652 | 1/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | TET3 | O43151 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25294721 | 1.00 | KDM4E (0.45) | KDM4EKDM5AKDM3AJMJD1CKDM5B | |
| SCHEMBL24921054 | 0.86 | ALDH1A1 (0.39) | KDM4EKDM5AKDM5BHCAR2L3MBTL1 | |
| SCHEMBL6305112 | 0.85 | NNMT (0.39) | KDM4EKDM5AKDM3AJMJD1CKDM5B | |
| SCHEMBL9952304 | 0.80 | KDM4E (0.49) | KDM4EKDM5AKDM3AJMJD1CKDM5B | |
| SCHEMBL31132583 | 0.79 | KDM4E (0.39) | KDM4EKDM5AKDM3AJMJD1CKDM5B | |
| SCHEMBL18036607 | 0.78 | KDM4E (0.50) | KDM4EKDM5AKDM3AJMJD1CKDM5B | |
| SCHEMBL31229428 | 0.77 | KDM4E (0.42) | KDM4EKDM5AKDM3AJMJD1CHCAR2 | |
| SCHEMBL25176793 | 0.77 | KDM4E (0.49) | KDM4EKDM5AKDM3AJMJD1CKDM5B | |
| SCHEMBL7368934 | 0.77 | KDM4E (0.49) | KDM4EKDM5AKDM3AJMJD1CKDM5B | |
| SCHEMBL31053756 | 0.77 | KDM4E (0.49) | KDM4EKDM5AKDM3AJMJD1CKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184152-A1 | FUSED RING SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2022-09-09 | — | — | WO | disclosed |