Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | KDM5A | P29375 | 2/20 | 0.49 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.49 |
| ▸ | JMJD1C | Q15652 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | TET3 | O43151 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18036607 | 0.82 | KDM4E (0.50) | KDM4EKDM5AKDM3AJMJD1CALOX15 | |
| SCHEMBL25176793 | 0.81 | KDM4E (0.49) | KDM4EKDM5AKDM3AJMJD1CALOX15 | |
| SCHEMBL31053756 | 0.81 | KDM4E (0.49) | KDM4EKDM5AKDM3AJMJD1CALOX15 | |
| SCHEMBL9952304 | 0.81 | KDM4E (0.49) | KDM4EKDM5AKDM3AJMJD1CALOX15 | |
| SCHEMBL30069017 | 0.77 | KDM4E (0.45) | KDM4EKDM5AKDM3AJMJD1CALOX15 | |
| SCHEMBL25294721 | 0.77 | KDM4E (0.45) | KDM4EKDM5AKDM3AJMJD1CALOX15 | |
| SCHEMBL3281281 | 0.75 | KDM4E (0.51) | KDM4EKDM5AKDM3AJMJD1CALOX15 | |
| SCHEMBL7066012 | 0.74 | ALDH1A1 (0.46) | KDM4EKDM5AKDM3AJMJD1CALOX15 | |
| SCHEMBL1397438 | 0.74 | KDM4E (0.46) | KDM4EKDM5AKDM3AJMJD1CALOX15 | |
| SCHEMBL319105 | 0.74 | KDM4E (0.53) | KDM4EKDM5AKDM3AJMJD1CALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691329-A | Compounds containing basic and acidic termini useful as fibrinogen receptor antagonists | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-11-25 | — | — | US | disclosed |
| US-5563158-A | CARDIOVASCULAR DISORDERS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| WO-1995018111-A1 | COMPOUNDS CONTAINING BASIC AND ACIDIC TERMINI USEFUL AS FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-07-06 | — | — | WO | disclosed |