Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | MMP1 | P03956 | 4/20 | 0.64 |
| ▸ | MMP2 | P08253 | 4/20 | 0.64 |
| ▸ | MMP9 | P14780 | 4/20 | 0.64 |
| ▸ | EGFR | P00533 | 1/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.57 |
| ▸ | KDM1A | O60341 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL296725 | 0.80 | SMN1; SMN2 (0.77) | RAB9ASMN1; SMN2MAPTMMP1MMP2 | |
| SCHEMBL29644891 | 0.79 | RAB9A (0.62) | RAB9ASMN1; SMN2MAPTMMP1MMP2 | |
| SCHEMBL30970349 | 0.77 | KDM4E (0.62) | SMN1; SMN2MAPTALDH1A1KDM4EGAA | |
| SCHEMBL7663681 | 0.77 | MMP1 (0.72) | RAB9ASMN1; SMN2MAPTMMP1MMP2 | |
| SCHEMBL31068007 | 0.76 | KMT2A (0.55) | RAB9ASMN1; SMN2MAPTMMP1MMP2 | |
| SCHEMBL27770381 | 0.75 | MMP1 (0.80) | RAB9ASMN1; SMN2MAPTMMP1MMP2 | |
| SCHEMBL13675885 | 0.73 | TRPV1 (1.00) | RAB9ASMN1; SMN2MAPTMMP1MMP2 | |
| SCHEMBL31068025 | 0.73 | GPR183 (0.42) | RAB9ASMN1; SMN2MAPTMMP1MMP2 | |
| SCHEMBL31068020 | 0.72 | SMN1; SMN2 (0.71) | RAB9ASMN1; SMN2MAPTMMP1MMP2 | |
| SCHEMBL4787813 | 0.72 | MAPT (0.61) | RAB9ASMN1; SMN2MAPTPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4351553-A1 | NOVEL ANTI-FIBROTIC DRUGS | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH (DE) | 2024-04-17 | — | — | EP | disclosed |
| WO-2022258792-A1 | NOVEL ANTI-FIBROTIC DRUGS | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2022-12-15 | — | — | WO | disclosed |