Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | MMP1 | P03956 | 4/20 | 0.59 |
| ▸ | MMP2 | P08253 | 4/20 | 0.59 |
| ▸ | MMP9 | P14780 | 4/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | KDM1A | O60341 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29644895 | 0.83 | MMP1 (0.60) | RAB9ASMN1; SMN2MAPTMMP1MMP2 | |
| SCHEMBL29644890 | 0.83 | PTPN1 (0.59) | RAB9ASMN1; SMN2MAPTMMP1MMP2 | |
| SCHEMBL29644900 | 0.83 | PTPN1 (0.59) | RAB9ASMN1; SMN2MAPTMMP1MMP2 | |
| SCHEMBL29644898 | 0.82 | MAPT (0.61) | RAB9ASMN1; SMN2MAPTMMP1MMP2 | |
| SCHEMBL29644902 | 0.80 | KDM1A (0.61) | MAPTTRPV1PTPN1MEN1KMT2A | |
| SCHEMBL30069263 | 0.79 | RAB9A (0.70) | RAB9ASMN1; SMN2MAPTMMP1MMP2 | |
| SCHEMBL29644884 | 0.78 | TRPV1 (0.61) | RAB9ASMN1; SMN2MAPTMMP1MMP2 | |
| SCHEMBL29644889 | 0.77 | MAPT (0.56) | RAB9ASMN1; SMN2MAPTMMP1MMP2 | |
| SCHEMBL296725 | 0.77 | SMN1; SMN2 (0.77) | RAB9ASMN1; SMN2MAPTMMP1MMP2 | |
| SCHEMBL16694311 | 0.76 | ABCG2 (0.62) | MAPTPTPN1MEN1KMT2APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096235-B | 2, 2-dimethyl benzopyran derivative and preparation method and application thereof | 沈阳药科大学 | 2022-06-21 | — | — | CN | disclosed |