Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 9/20 | 0.34 |
| ▸ | MMP2 | P08253 | 3/20 | 0.34 |
| ▸ | MMP8 | P22894 | 3/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | VIPR2 | P41587 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300470 | 1.00 | MMP1 (0.40) | MMP1CNR2CNR1MMP9MMP2 | |
| SCHEMBL300546 | 0.93 | VIPR2 (0.36) | MMP1CNR2CNR1MMP9MMP2 | |
| SCHEMBL177037 | 0.88 | CNR1 (0.44) | MMP1CNR2CNR1MMP9MMP2 | |
| SCHEMBL176725 | 0.88 | CNR1 (0.44) | MMP1CNR2CNR1MMP9MMP2 | |
| SCHEMBL300734 | 0.83 | ALDH1A1 (0.38) | CNR2 | |
| SCHEMBL176680 | 0.80 | CNR1 (0.43) | CNR2CNR1VIPR2DHODHRORC | |
| SCHEMBL176682 | 0.80 | CNR1 (0.43) | CNR2CNR1VIPR2DHODHRORC | |
| SCHEMBL300360 | 0.79 | CNR2 (0.46) | CNR2 | |
| SCHEMBL300745 | 0.78 | CNR1 (0.39) | CNR2CNR1MMP9MMP2 | |
| SCHEMBL300716 | 0.78 | CNR1 (0.39) | CNR2CNR1MMP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |