Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PDE9A | O76083 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300469 | 0.92 | CYP3A4 (0.40) | CNR2MAPK1FKBP1ABCHEACHE | |
| SCHEMBL300678 | 0.91 | CNR2 (0.48) | CNR2MAPK1FKBP1A | |
| SCHEMBL176638 | 0.87 | CNR2 (0.48) | CNR2MEN1KMT2AMAPK1PDE9A | |
| SCHEMBL176620 | 0.87 | CNR2 (0.48) | CNR2MEN1KMT2AMAPK1PDE9A | |
| SCHEMBL300734 | 0.87 | ALDH1A1 (0.38) | CNR2THRB | |
| SCHEMBL300521 | 0.82 | CNR2 (0.43) | CNR2 | |
| SCHEMBL300704 | 0.79 | MMP1 (0.40) | CNR2 | |
| SCHEMBL300470 | 0.79 | MMP1 (0.40) | CNR2 | |
| SCHEMBL300549 | 0.79 | THRB (0.41) | MEN1KMT2APOLBTHRB | |
| SCHEMBL176782 | 0.79 | MAPK1 (0.45) | CNR2MAPK1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |