Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.39 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.39 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.36 |
| ▸ | TUBB | P07437 | 3/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3298576 | 0.78 | ENPP2 (0.54) | ENPP2ORAI1ORAI2ORAI3TUBB4A | |
| SCHEMBL481354 | 0.77 | CYP3A4 (0.48) | PRKDCCYP3A4MAPTTSHRKDM4E | |
| SCHEMBL3480772 | 0.74 | ENPP2 (0.46) | ENPP2ORAI1ORAI2ORAI3TUBB4A | |
| SCHEMBL30905973 | 0.73 | ENPP2 (0.45) | ENPP2ORAI1ORAI2ORAI3TUBB4A | |
| SCHEMBL2914602 | 0.73 | ENPP2 (0.45) | ENPP2ORAI1ORAI2ORAI3TUBB4A | |
| SCHEMBL2567303 | 0.73 | ENPP2 (0.45) | ENPP2ORAI1ORAI2ORAI3TUBB4A | |
| SCHEMBL31253228 | 0.73 | ENPP2 (0.45) | ENPP2ORAI1ORAI2ORAI3TUBB4A | |
| SCHEMBL15728768 | 0.72 | TUBB4A (0.44) | ENPP2ORAI1ORAI2ORAI3TUBB4A | |
| SCHEMBL28211962 | 0.72 | HTR2A (0.50) | PRKDCCYP3A4MAPTTSHRKDM4E | |
| SCHEMBL481337 | 0.72 | HTR2A (0.54) | CYP3A4MAPTTSHRALDH1A1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8822720-B2 | Method for the organocatalytic activation of carboxylic acids for chemical, reactions using orthosubstituted arylboronic acids | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2014-09-02 | — | — | US | claimed |
| US-20100197960-A1 | METHOD FOR THE ORGANOCATALYTIC ACTIVATION OF CARBOXYLIC ACIDS FOR CHEMICAL, REACTIONS USING ORTHOSUBSTITUTED ARYLBORONIC ACIDS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2010-08-05 | — | — | US | claimed |
| EP-2193134-A1 | METHOD FOR THE ORGANOCATALYTIC ACTIVATION OF CARBOXYLIC ACIDS FOR CHEMICAL REACTIONS USING ORTHOSUBSTITUTED ARYLBORONIC ACIDS | The Governors Of The University Of Alberta (CA) | 2010-06-09 | — | — | EP | claimed |
| WO-2009030022-A1 | METHOD FOR THE ORGANOCATALYTIC ACTIVATION OF CARBOXYLIC ACIDS FOR CHEMICAL REACTIONS USING ORTHOSUBSTITUTED ARYLBORONIC ACIDS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2009-03-12 | — | — | WO | claimed |
| US-8822720-B2 | Method for the organocatalytic activation of carboxylic acids for chemical, reactions using orthosubstituted arylboronic acids | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2014-09-02 | — | — | US | disclosed |
| US-8822720-B2 | Method for the organocatalytic activation of carboxylic acids for chemical, reactions using orthosubstituted arylboronic acids | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2014-09-02 | — | — | US | disclosed |
| US-8822720-B2 | Method for the organocatalytic activation of carboxylic acids for chemical, reactions using orthosubstituted arylboronic acids | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2014-09-02 | — | — | US | disclosed |
| US-20100197960-A1 | METHOD FOR THE ORGANOCATALYTIC ACTIVATION OF CARBOXYLIC ACIDS FOR CHEMICAL, REACTIONS USING ORTHOSUBSTITUTED ARYLBORONIC ACIDS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2010-08-05 | — | — | US | disclosed |
| US-20100197960-A1 | METHOD FOR THE ORGANOCATALYTIC ACTIVATION OF CARBOXYLIC ACIDS FOR CHEMICAL, REACTIONS USING ORTHOSUBSTITUTED ARYLBORONIC ACIDS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2010-08-05 | — | — | US | disclosed |
| US-20100197960-A1 | METHOD FOR THE ORGANOCATALYTIC ACTIVATION OF CARBOXYLIC ACIDS FOR CHEMICAL, REACTIONS USING ORTHOSUBSTITUTED ARYLBORONIC ACIDS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2010-08-05 | — | — | US | disclosed |
| EP-2193134-A1 | METHOD FOR THE ORGANOCATALYTIC ACTIVATION OF CARBOXYLIC ACIDS FOR CHEMICAL REACTIONS USING ORTHOSUBSTITUTED ARYLBORONIC ACIDS | The Governors Of The University Of Alberta (CA) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009030022-A1 | METHOD FOR THE ORGANOCATALYTIC ACTIVATION OF CARBOXYLIC ACIDS FOR CHEMICAL REACTIONS USING ORTHOSUBSTITUTED ARYLBORONIC ACIDS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2009-03-12 | — | — | WO | disclosed |
| WO-2009030022-A1 | METHOD FOR THE ORGANOCATALYTIC ACTIVATION OF CARBOXYLIC ACIDS FOR CHEMICAL REACTIONS USING ORTHOSUBSTITUTED ARYLBORONIC ACIDS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2009-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197960-A1 | METHOD FOR THE ORGANOCATALYTIC ACTIVATION OF CARBOXYLIC ACIDS FOR CHEMICAL, REACTIONS USING ORTHOSUBSTITUTED ARYLBORONIC ACIDS | AOC2, AOC3, OXER1 | ENPP2 3526/4885ORAI1 1108/4885ORAI2 1271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.