Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 9/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300698 | 0.92 | LIPE (0.48) | LIPENPC1HTTCNR1 | |
| SCHEMBL176669 | 0.86 | SMN1; SMN2 (0.46) | LIPESMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL176670 | 0.86 | SMN1; SMN2 (0.46) | LIPESMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL300459 | 0.77 | CNR2 (0.51) | LIPEKDM4EMAPTCNR1MEN1 | |
| SCHEMBL176623 | 0.77 | NPC1 (0.46) | NPC1HTTCNR1 | |
| SCHEMBL176622 | 0.77 | NPC1 (0.46) | NPC1HTTCNR1 | |
| SCHEMBL300525 | 0.76 | CNR1 (0.46) | ALDH1A1MAPK1LMNAL3MBTL1CNR1 | |
| SCHEMBL300660 | 0.76 | CNR1 (0.46) | ALDH1A1MAPK1LMNAL3MBTL1CNR1 | |
| SCHEMBL300665 | 0.75 | MAPK1 (0.35) | MAPK1NPC1HTTCNR1 | |
| SCHEMBL300543 | 0.75 | MAPK1 (0.35) | MAPK1NPC1HTTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |