Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | HAO2 | Q9NYQ3 | 1/20 | 0.40 |
| ▸ | GAK | O14976 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | MARK1 | Q9P0L2 | 1/20 | 0.37 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | RPA1 | P27694 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29812163 | 0.74 | HAO2 (0.52) | HAO2GAKPDGFRBKITFLT3 | |
| SCHEMBL2374242 | 0.71 | ALDH1A1 (0.45) | AXLKEAP1ALPLRAB9AMAPK14 | |
| SCHEMBL14519615 | 0.70 | MAPK14 (0.55) | MAPK14 | |
| SCHEMBL26502927 | 0.69 | MAPT (0.46) | RAB9AMAPK14KDM4EALDH1A1HPGD | |
| SCHEMBL168203 | 0.69 | TUBB4A (0.43) | HAO2GAKPDGFRBKITFLT3 | |
| SCHEMBL28310139 | 0.68 | HAO2 (0.62) | HAO2KITCA12ALPLRPA1 | |
| SCHEMBL6440359 | 0.66 | ALDH1A1 (0.41) | RAB9AMAPK14KDM4EALDH1A1MAPK1 | |
| SCHEMBL167755 | 0.66 | IRAK4 (0.39) | HAO2GAKPDGFRBKITFLT3 | |
| SCHEMBL20376614 | 0.66 | PTGS1 (0.40) | FLT3MKNK2STK17AMAPK14KDM4E | |
| SCHEMBL168619 | 0.65 | GRM2 (0.41) | GAKPDGFRBKITFLT3MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283369-A1 | MODULATORS OF PROTEIN KINASES | VIBLIOME THERAPEUTICS, LLC (US) | 2023-01-12 | — | — | WO | disclosed |