Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23926986 | 1.00 | MAPK14 (0.36) | MAPK14TRPA1BRD4MEN1KMT2A | |
| SCHEMBL25141902 | 0.81 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL23927078 | 0.80 | HSPB1 (0.48) | MEN1KMT2A | |
| SCHEMBL30257867 | 0.76 | — | — | |
| SCHEMBL30079509 | 0.74 | KEAP1 (0.49) | MEN1KMT2A | |
| SCHEMBL31157938 | 0.74 | KEAP1 (0.31) | — | |
| SCHEMBL21116508 | 0.73 | HTR1A (0.39) | — | |
| SCHEMBL23927086 | 0.72 | GABRP (0.36) | TRPA1 | |
| SCHEMBL23927004 | 0.72 | KEAP1 (0.35) | — | |
| SCHEMBL30059265 | 0.72 | MEN1 (0.40) | MAPK14TRPA1BRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115380032-A | KV3 enhancers for the treatment of cognitive disorders | 豪夫迈·罗氏有限公司 | 2022-11-22 | — | — | CN | disclosed |