Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 10/20 | 0.54 |
| ▸ | PKLR | P30613 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | IL1RN | P18510 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28919060 | 1.00 | PKM (0.54) | PKMPKLRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL30080374 | 0.87 | NR1H4 (0.54) | PKMALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL28919042 | 0.87 | NR1H4 (0.54) | PKMALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL28919037 | 0.84 | MAPT (0.52) | PKMPKLRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28919074 | 0.80 | PKM (0.62) | PKMPKLRALDH1A1POLBMAPT | |
| SCHEMBL28919080 | 0.79 | PKM (0.48) | PKMPKLRALDH1A1POLB | |
| SCHEMBL28919025 | 0.77 | NR1H4 (0.58) | PKMALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL30080392 | 0.77 | PKM (0.60) | PKMPKLRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL30080500 | 0.77 | NR1H4 (0.58) | PKMALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL28919016 | 0.75 | PKLR (0.65) | PKMPKLRALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521272-B | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2023-07-21 | — | — | CN | disclosed |
| CN-115521272-A | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2022-12-27 | — | — | CN | disclosed |