Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | IL1RN | P18510 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30080374 | 1.00 | NR1H4 (0.54) | NR1H4CNR1TDP1AKR1C3AKR1C2 | |
| SCHEMBL30080500 | 0.90 | NR1H4 (0.58) | NR1H4CNR1TDP1AKR1C3AKR1C2 | |
| SCHEMBL28919025 | 0.90 | NR1H4 (0.58) | NR1H4CNR1TDP1AKR1C3AKR1C2 | |
| SCHEMBL28919060 | 0.87 | PKM (0.54) | TDP1ALDH1A1MAPTIL1RNPOLB | |
| SCHEMBL30080265 | 0.87 | PKM (0.54) | TDP1ALDH1A1MAPTIL1RNPOLB | |
| SCHEMBL28919043 | 0.84 | ALDH1A1 (0.52) | NR1H4ALDH1A1MAPT | |
| SCHEMBL28919039 | 0.80 | CNR1 (0.53) | NR1H4CNR1ALDH1A1MAPTPOLB | |
| SCHEMBL28919078 | 0.79 | MEN1 (0.43) | NR1H4CNR1TDP1AKR1C3AKR1C2 | |
| SCHEMBL30080496 | 0.76 | NR1H4 (0.54) | NR1H4CNR1ALDH1A1MAPTPOLB | |
| SCHEMBL1892800 | 0.76 | NR1H4 (0.80) | NR1H4CNR1TDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521272-B | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2023-07-21 | — | — | CN | disclosed |
| CN-115521272-A | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2022-12-27 | — | — | CN | disclosed |