Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 8/20 | 0.60 |
| ▸ | PKLR | P30613 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30080496 | 0.85 | NR1H4 (0.54) | PKMALDH1A1SMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL30080582 | 0.84 | PKM (0.60) | PKMPKLRALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL2239830 | 0.78 | PKM (1.00) | PKMPKLR | |
| SCHEMBL8048603 | 0.78 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2TSHRKMT2A | |
| SCHEMBL2959432 | 0.77 | CHRM4 (0.52) | PKMALDH1A1SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL28919074 | 0.77 | PKM (0.62) | PKMPKLRALDH1A1TSHR | |
| SCHEMBL28919060 | 0.77 | PKM (0.54) | PKMPKLRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL30080265 | 0.77 | PKM (0.54) | PKMPKLRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL17800942 | 0.76 | PKM (0.74) | PKMPKLRALDH1A1LMNA | |
| SCHEMBL19871301 | 0.75 | PKM (0.79) | PKMPKLRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521272-B | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2023-07-21 | — | — | CN | disclosed |
| CN-115521272-A | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2022-12-27 | — | — | CN | disclosed |