Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 5/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 9/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 8/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2253695 | 0.83 | NR1H2 (0.44) | STSNR1H2NR1H3PARP1MAPK1 | |
| SCHEMBL4265890 | 0.81 | HTR6 (0.41) | NR1H2NR1H3PARP1ALDH1A1TSHR | |
| SCHEMBL1563776 | 0.80 | STS (0.35) | STSPARP1ALDH1A1TSHRLMNA | |
| SCHEMBL30945108 | 0.79 | NR1H2 (0.40) | STSNR1H2PARP1 | |
| SCHEMBL30032878 | 0.76 | MAPT (0.47) | PARP1ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL30911841 | 0.73 | PARP1 (0.40) | PARP1HPGDSMN1; SMN2 | |
| SCHEMBL1673503 | 0.73 | MEN1 (0.43) | STSNR1H2NR1H3PARP1ALDH1A1 | |
| SCHEMBL4325057 | 0.72 | NR1H2 (0.49) | NR1H2NR1H3PARP1MAPK1RXRA | |
| SCHEMBL874416 | 0.72 | NR1H2 (0.49) | NR1H2NR1H3PARP1MAPK1RXRA | |
| SCHEMBL22285173 | 0.72 | NR1H2 (0.49) | NR1H2NR1H3PARP1MAPK1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521272-B | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2023-07-21 | — | — | CN | disclosed |
| CN-115521272-A | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2022-12-27 | — | — | CN | disclosed |