Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28660308 | 1.00 | MAPT (0.32) | MAPTCRHBPHTTCRHR2PIK3CA | |
| SCHEMBL30083014 | 0.86 | ALDH1A1 (0.35) | MAPTHTTPIK3CAHIF1AEPAS1 | |
| SCHEMBL28664582 | 0.86 | ALDH1A1 (0.35) | MAPTHTTPIK3CAHIF1AEPAS1 | |
| SCHEMBL30083021 | 0.82 | P2RX3 (0.38) | MAPTPIK3CAP2RX3P2RX2 | |
| SCHEMBL30148695 | 0.77 | ALDH1A1 (0.41) | MAPTHTTALDH1A1LMNA | |
| SCHEMBL30543269 | 0.71 | MAPT (0.40) | MAPTCRHBPHTTCRHR2ALDH1A1 | |
| SCHEMBL116509 | 0.71 | MAPT (0.40) | MAPTCRHBPHTTCRHR2ALDH1A1 | |
| SCHEMBL24449303 | 0.71 | RORC (0.40) | MAPTHTTALDH1A1LMNAAMY1A | |
| SCHEMBL30083022 | 0.69 | P2RX3 (0.35) | MAPTPIK3CAP2RX3P2RX2 | |
| SCHEMBL24449302 | 0.69 | RORC (0.41) | MAPTHTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113698388-B | 6-oxo-1, 6-dihydropyridine derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2022-11-22 | — | — | CN | disclosed |