Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | KCNN3 | Q9UGI6 | 4/20 | 0.36 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.36 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.31 |
| ▸ | PLK4 | O00444 | 2/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CCNK | O75909 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30083621 | 0.88 | KCNN3 (0.41) | CSNK2A2KCNN3KCNN1KCNN2CDK2 | |
| SCHEMBL30083487 | 0.86 | KCNN3 (0.37) | KCNN3KCNN1KCNN2CDK2KDM4E | |
| SCHEMBL24792474 | 0.84 | CDK7 (0.46) | CSNK2A2CDK2GSK3BDPP4CDK7 | |
| SCHEMBL30872090 | 0.84 | KCNN3 (0.38) | KCNN3KCNN1KCNN2CDK2KDM4E | |
| SCHEMBL30083469 | 0.84 | GPR39 (0.41) | CSNK2A2KCNN3KCNN1KCNN2CDK2 | |
| SCHEMBL24792976 | 0.81 | CDK7 (0.49) | CSNK2A2CDK2GSK3BCDK7CCNT1 | |
| SCHEMBL30872099 | 0.75 | KCNN3 (0.39) | KCNN3KCNN1KCNN2CDK2KDM4E | |
| SCHEMBL30083523 | 0.74 | KCNN3 (0.44) | KCNN3KCNN1KCNN2CDK2KDM4E | |
| SCHEMBL30083507 | 0.73 | GPR39 (0.41) | KCNN3KCNN1KCNN2CDK2GSK3B | |
| SCHEMBL24792726 | 0.72 | CDK2 (0.42) | CSNK2A2CDK2GSK3BCDK7CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940427-A | Substituted pyrazolo [1,5-a ] pyrimidine-7-amine compounds as CDK inhibitors and therapeutic uses thereof | 卡里克治疗有限公司 | 2024-04-26 | — | — | CN | disclosed |
| EP-4355426-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE COMPOUNDS AS CDK INHIBITORS AND THEIR THERAPEUTIC USE | Carrick Therapeutics Limited (IE) | 2024-04-24 | — | — | EP | disclosed |
| WO-2022263604-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE COMPOUNDS AS CDK INHIBITORS AND THEIR THERAPEUTIC USE | Carrick Therapeutics Limited (IE) | 2022-12-22 | — | — | WO | disclosed |