Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.35 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.34 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.33 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL720130 | 1.00 | ALDH1A1 (0.38) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| SCHEMBL4075601 | 0.92 | ALDH1A1 (0.38) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| SCHEMBL4048510 | 0.83 | GAA (0.45) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| SCHEMBL30093444 | 0.83 | GAA (0.45) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| SCHEMBL2999828 | 0.80 | TERT (0.45) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| SCHEMBL12121770 | 0.76 | TGFBR1 (0.44) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| SCHEMBL22366924 | 0.76 | NPC1 (0.38) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| SCHEMBL22304452 | 0.76 | DYRK1A (0.42) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| SCHEMBL5541837 | 0.76 | NPC1 (0.41) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| SCHEMBL4052274 | 0.76 | RIPK2 (0.39) | ALDH1A1HSD17B10NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119424423-A | 4-Aminobut-2-enamide derivatives and salts thereof | 大鹏药品工业株式会社 | 2025-02-14 | — | — | CN | disclosed |
| CN-115768771-A | Arylsulfonyl derivatives and their use as muscarinic acetylcholine receptor M5 inhibitors | 范德堡大学 | 2023-03-07 | — | — | CN | disclosed |
| CN-115551500-A | 4-aminobut-2-enamide derivatives and salts thereof | 大鹏药品工业株式会社 | 2022-12-30 | — | — | CN | disclosed |