Selenium

Selenium

SCHEMBL30089787

N#Cc1cc(=O)c2ccccc2o1.[Se]

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS O95271 7/20 0.56
CYP2A6 P11509 1/20 0.55
RAB9A P51151 5/20 0.50
NPC1 O15118 5/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
PARP1 P09874 3/20 0.50
HPGD P15428 3/20 0.50
TNKS2 Q9H2K2 3/20 0.50
GABRP O00591 2/20 0.50
GABRD O14764 2/20 0.50
GABRA1 P14867 2/20 0.50
GABRB1 P18505 2/20 0.50
GABRG2 P18507 2/20 0.50
GABRB3 P28472 2/20 0.50
GABRA5 P31644 2/20 0.50
GABRA3 P34903 2/20 0.50
GABRA2 P47869 2/20 0.50
GABRB2 P47870 2/20 0.50
GABRA4 P48169 2/20 0.50
GABRE P78334 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6956680 0.98 TNKS (0.58) TNKSCYP2A6RAB9ANPC1SMN1; SMN2
SCHEMBL3081542 0.81 TNKS (0.53) TNKSRAB9ANPC1SMN1; SMN2PARP1
SCHEMBL11550404 0.77 AHR (0.57) CYP2A6RAB9ANPC1HPGDCA1
SCHEMBL9635627 0.76 ALDH1A1 (0.55) TNKSCYP2A6PARP1HPGDTNKS2
SCHEMBL6957384 0.76 ADCY1 (0.55) TNKSRAB9ANPC1SMN1; SMN2HPGD
SCHEMBL6961168 0.76 ALDH1A1 (0.55) TNKSSMN1; SMN2PARP1HPGDTNKS2
SCHEMBL29382214 0.74 TNKS (0.51) TNKSRAB9ANPC1SMN1; SMN2PARP1
SCHEMBL24046926 0.73 TNKS (0.45) TNKSRAB9ANPC1SMN1; SMN2PARP1
SCHEMBL6956169 0.72 AR (0.61) CYP2A6SMN1; SMN2HPGDCYP3A4AR
SCHEMBL6836790 0.72 PPARG (0.58) TNKSRAB9ANPC1SMN1; SMN2PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110563632-B Electrophilic selenocyanization reagent and preparation method and application thereof 南宁师范大学 2022-11-25 CN disclosed