Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 11/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5847284 | 0.78 | PDK2 (0.42) | PDK2LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL23655327 | 0.78 | PDK2 (0.61) | PDK2LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL5487698 | 0.78 | PDK2 (0.42) | PDK2LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL5846726 | 0.78 | PDK2 (0.63) | PDK2LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL5848508 | 0.77 | PDK2 (0.50) | PDK2KDM4EALDH1A1RAB9A | |
| SCHEMBL14691084 | 0.76 | PDK2 (0.33) | PDK2 | |
| SCHEMBL16346749 | 0.74 | ALDH1A1 (0.41) | PDK2LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL5846694 | 0.74 | ALDH1A1 (0.41) | PDK2LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL16346844 | 0.74 | ALDH1A1 (0.41) | PDK2LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL16995983 | 0.74 | HTR7 (0.47) | PDK2KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535703-B2 | Methanesulfonic acid mediated solvent free synthesis of conjugated porous polymer networks | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2022-12-27 | — | — | US | disclosed |