Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 13/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5491988 | 0.83 | PDK2 (0.36) | PDK2LMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL5847284 | 0.81 | PDK2 (0.42) | PDK2LMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL5846726 | 0.81 | PDK2 (0.63) | PDK2LMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL23655327 | 0.81 | PDK2 (0.61) | PDK2LMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL5492754 | 0.78 | MEN1 (0.57) | PDK2LMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL1495181 | 0.78 | ESR1 (0.44) | PDK2LMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL30089997 | 0.78 | PDK2 (0.41) | PDK2LMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL16995983 | 0.77 | HTR7 (0.47) | PDK2KMT2ATSHRALDH1A1 | |
| SCHEMBL19092436 | 0.74 | PDK2 (0.54) | PDK2LMNAMAPTSMN1; SMN2ESR1 | |
| SCHEMBL18079823 | 0.74 | HTR1A (0.46) | PDK2CYP1A2CYP2C9TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7227027-B2 | Carbazole derivative and its use in electroluminescent devices | TSINGHUA UNIVERSITY (CH) | 2007-06-05 | — | — | US | disclosed |
| US-20050127826-A1 | Carbazole derivative and its use in electroluminescent devices | BEIJING VISIONOX TECHNOLOGY CO., LTD. (CN) | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050127826-A1 | Carbazole derivative and its use in electroluminescent devices | OCIAD1, OCIAD2, EED | PDK2 229/4885LMNA 3413/4885MAPT 722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.