Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23927449 | 1.00 | ALOX5 (0.40) | ALOX5MEN1KMT2AMAPTPTGES | |
| SCHEMBL15964605 | 0.88 | NPC1 (0.43) | ALOX5MEN1KMT2APTGESALDH1A1 | |
| SCHEMBL23927459 | 0.83 | KDM4E (0.42) | MRGPRX4ALDH1A1CYP1A2TP53P2RX7 | |
| SCHEMBL30091516 | 0.83 | P2RX7 (0.37) | MEN1KMT2AMAPTALDH1A1RXFP1 | |
| SCHEMBL23927439 | 0.83 | P2RX7 (0.37) | MEN1KMT2AMAPTALDH1A1RXFP1 | |
| SCHEMBL23927507 | 0.82 | HPGD (0.40) | MEN1KMT2AALDH1A1CYP1A2TP53 | |
| SCHEMBL17324405 | 0.82 | KMT2A (0.50) | ALOX5MEN1KMT2AMAPTPTGES | |
| SCHEMBL23189116 | 0.79 | TSHR (0.44) | MEN1KMT2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL23927454 | 0.79 | ALOX15 (0.45) | MAPTALDH1A1CYP1A2PDE3BPDE3A | |
| SCHEMBL30091646 | 0.79 | ALOX15 (0.45) | MAPTALDH1A1CYP1A2PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166116-B | Amido bridged heterocyclic compound, and composition and application thereof | 北京赛特明强医药科技有限公司 | 2022-12-27 | — | — | CN | disclosed |