Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 6/20 | 0.40 |
| ▸ | POLR1A | O95602 | 6/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599479 | 0.94 | PARP1 (0.43) | TYK2PARP1SHMT2ALDH1A1POLB | |
| SCHEMBL598792 | 0.79 | PARP1 (0.42) | PARP1SHMT2ALDH1A1POLBMAPT | |
| SCHEMBL598268 | 0.79 | ALDH1A1 (0.48) | SHMT2ALDH1A1POLBMAPTTSHR | |
| Hydrochloric Acid SCHEMBL599366 | 0.78 | ALDH1A1 (0.47) | SHMT2ALDH1A1POLBMAPTTSHR | |
| SCHEMBL599063 | 0.78 | ALDH1A1 (0.49) | SHMT2ALDH1A1MAPTTSHR | |
| Hydrochloric Acid SCHEMBL3008541 | 0.76 | GAA (0.47) | ALDH1A1POLBMAPT | |
| SCHEMBL598043 | 0.76 | ALDH1A1 (0.40) | SHMT2ALDH1A1MAPTTSHR | |
| SCHEMBL598435 | 0.76 | NTRK1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL3006169 | 0.76 | KDM4E (0.42) | POLR1AKCNH2SHMT2ALDH1A1POLB | |
| SCHEMBL598771 | 0.74 | KMT2A (0.41) | ALDH1A1MAPTNPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197723-A1 | BICYCLIC COMPOUNDS AND METHODS OF MAKING AND USING SAME | NANOSHIFT, LLC | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197723-A1 | BICYCLIC COMPOUNDS AND METHODS OF MAKING AND USING SAME | HTR2C, HTR3A, HTR3C | MTNR1A 192/4885TYK2 3353/4885POLR1A 1891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.