Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDIA6 | Q15084 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 6/20 | 0.39 |
| ▸ | CA2 | P00918 | 6/20 | 0.39 |
| ▸ | CA9 | Q16790 | 6/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23833549 | 1.00 | PDIA6 (0.39) | PDIA6CA12CA1CA2CA9 | |
| SCHEMBL30094638 | 0.86 | L3MBTL1 (0.42) | KDM4EGAAMAPTALDH1A1NNMT | |
| SCHEMBL23833547 | 0.86 | L3MBTL1 (0.42) | KDM4EGAAMAPTALDH1A1NNMT | |
| SCHEMBL25518454 | 0.83 | CDK1 (0.37) | KDM4EGAAMAPTALDH1A1NNMT | |
| SCHEMBL31028749 | 0.77 | UHRF1 (0.48) | PDIA6CA12CA1CA2CA9 | |
| SCHEMBL23833536 | 0.77 | HTT (0.43) | KDM4EGAAMAPTALDH1A1LMNA | |
| SCHEMBL23833576 | 0.77 | KDM4E (0.55) | KDM4EGAAMAPTALDH1A1LMNA | |
| SCHEMBL25518530 | 0.77 | KDM4E (0.33) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL23833599 | 0.76 | ALDH1A1 (0.48) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL3620179 | 0.74 | NOS3 (0.50) | KDM4EGAAMAPTALDH1A1NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121426-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND USE | Akebia Therapeutics Inc. (US) | 2023-01-25 | — | — | EP | disclosed |