Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23833635 | 1.00 | NNMT (0.37) | NNMTALDH1A1KDM4EGAAMAPT | |
| SCHEMBL3620179 | 0.74 | NOS3 (0.50) | NNMTALDH1A1KDM4EGAAMAPT | |
| SCHEMBL23833609 | 0.72 | — | — | |
| SCHEMBL23832350 | 0.70 | KDM4E (0.42) | NNMTALDH1A1KDM4EGAAMAPT | |
| SCHEMBL30096938 | 0.70 | KDM4E (0.42) | NNMTALDH1A1KDM4EGAAMAPT | |
| SCHEMBL24099889 | 0.69 | ALDH1A1 (0.42) | NNMTALDH1A1KDM4EGAAMAPT | |
| SCHEMBL4751919 | 0.69 | NNMT (0.37) | NNMTALDH1A1KDM4EGAAMAPT | |
| SCHEMBL20772252 | 0.69 | NNMT (0.37) | NNMTALDH1A1KDM4EGAAMAPT | |
| SCHEMBL20772266 | 0.69 | NNMT (0.37) | NNMTALDH1A1KDM4EGAAMAPT | |
| SCHEMBL23833547 | 0.68 | L3MBTL1 (0.42) | NNMTALDH1A1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121426-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND USE | Akebia Therapeutics Inc. (US) | 2023-01-25 | — | — | EP | disclosed |