Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 7/20 | 0.59 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22291660 | 1.00 | NNMT (0.59) | NNMTSIRT3TDP1GABRPGABRD | |
| SCHEMBL15547132 | 0.84 | GABRP (0.44) | NNMTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3752864 | 0.82 | GABRP (0.61) | NNMTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL15713423 | 0.82 | KCNQ3 (0.43) | NNMTTDP1GABRPGABRDGABRA1 | |
| SCHEMBL30414922 | 0.82 | KCNQ3 (0.43) | NNMTTDP1GABRPGABRDGABRA1 | |
| SCHEMBL30197143 | 0.80 | NNMT (0.62) | NNMTSIRT3TDP1GABRPGABRD | |
| SCHEMBL29799541 | 0.80 | NNMT (0.61) | NNMTSIRT6SLC2A1MKNK1MKNK2 | |
| SCHEMBL384113 | 0.80 | NNMT (0.61) | NNMTSIRT6SLC2A1MKNK1MKNK2 | |
| SCHEMBL5009904 | 0.80 | NNMT (0.62) | NNMTSIRT3TDP1GABRPGABRD | |
| SCHEMBL17362420 | 0.78 | SIRT6 (0.47) | NNMTTDP1GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009719-A2 | STABILITY-ENHANCING COMPOSITIONS AND METHODS OF PREPARING COMPOUNDS | FOGHORN THERAPEUTICS INC. (US) | 2023-02-02 | — | — | WO | disclosed |
| WO-2023009701-A2 | THERAPEUTIC REGIMENS OF A DEGRADER OF BRD9 | FOGHORN THERAPEUTICS INC. (US) | 2023-02-02 | — | — | WO | disclosed |
| WO-2023283263-A1 | CITRATE SALT, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME | FOGHORN THERAPEUTICS INC. (US) | 2023-01-12 | — | — | WO | disclosed |
| EP-4096651-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |