Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 4/20 | 0.38 |
| ▸ | HRH1 | P35367 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30097002 | 0.81 | LMNA (0.43) | LMNAPOLBSMN1; SMN2HRH2HRH1 | |
| SCHEMBL31173444 | 0.78 | MEN1 (0.46) | SMN1; SMN2HRH2HRH1KMT2APTGDR2 | |
| SCHEMBL17925988 | 0.74 | SMN1; SMN2 (0.45) | LMNAPOLBSMN1; SMN2HRH2HRH1 | |
| SCHEMBL30297607 | 0.70 | MAPT (0.43) | LMNAPOLBSMN1; SMN2HRH2HRH1 | |
| SCHEMBL9627031 | 0.70 | SMN1; SMN2 (0.50) | LMNAPOLBSMN1; SMN2HRH2HRH1 | |
| SCHEMBL9405372 | 0.70 | POLB (0.73) | LMNAPOLBSMN1; SMN2HRH2HRH1 | |
| SCHEMBL7832611 | 0.69 | GAA (0.54) | LMNAPOLBSMN1; SMN2HRH2HRH1 | |
| SCHEMBL29742051 | 0.69 | LMNA (0.43) | LMNAPOLBSMN1; SMN2HRH2HRH1 | |
| SCHEMBL30376374 | 0.69 | ABHD6 (0.41) | LMNAPOLBSMN1; SMN2HRH2HRH1 | |
| SCHEMBL29742093 | 0.69 | SMN1; SMN2 (0.40) | LMNAPOLBSMN1; SMN2HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4096667-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |