Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30097018 | 0.83 | ATM (0.44) | FAAHL3MBTL1RAB9AHPGDMAPT | |
| SCHEMBL26143921 | 0.80 | NAMPT (0.45) | L3MBTL1RAB9A | |
| SCHEMBL30097039 | 0.80 | NAMPT (0.45) | L3MBTL1RAB9A | |
| SCHEMBL30097049 | 0.78 | MAPKAPK2 (0.42) | FAAHL3MBTL1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL23705823 | 0.77 | IMPDH2 (0.44) | — | |
| SCHEMBL22366449 | 0.77 | L3MBTL1 (0.47) | FAAHL3MBTL1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL17017926 | 0.74 | L3MBTL1 (0.46) | FAAHL3MBTL1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL8507123 | 0.74 | HPGD (0.67) | L3MBTL1RAB9AHPGDKMT2AMEN1 | |
| SCHEMBL17017128 | 0.74 | L3MBTL1 (0.46) | FAAHL3MBTL1RAB9AHPGDKMT2A | |
| SCHEMBL30890579 | 0.73 | HPGD (0.65) | RAB9AHPGDKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4096667-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |