Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30097042 | 0.83 | TSHR (0.43) | MAPKAPK2SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL29673310 | 0.80 | KDM4A (0.42) | MAPKAPK2L3MBTL1BCHEMAPK1 | |
| SCHEMBL23705506 | 0.80 | KDM4A (0.42) | MAPKAPK2L3MBTL1BCHEMAPK1 | |
| SCHEMBL29673308 | 0.80 | KDM4A (0.42) | MAPKAPK2L3MBTL1BCHEMAPK1 | |
| SCHEMBL30097018 | 0.80 | ATM (0.44) | MAPKAPK2SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL23705919 | 0.79 | L3MBTL1 (0.36) | SMN1; SMN2NPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL30103111 | 0.79 | ALDH1A1 (0.36) | MAPKAPK2SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL30097047 | 0.78 | FAAH (0.44) | MAPKAPK2SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL17017926 | 0.78 | L3MBTL1 (0.46) | MAPKAPK2SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL30689837 | 0.77 | CNR1 (0.38) | SMN1; SMN2NPC1RAB9AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4096667-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |