Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 9/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17017926 | 0.86 | L3MBTL1 (0.46) | L3MBTL1HPGDACHETSHRMAPK1 | |
| SCHEMBL1695969 | 0.78 | HPGD (0.47) | L3MBTL1KDM4EHPGDHTTRAB9A | |
| SCHEMBL30758763 | 0.77 | ALDH1A1 (0.47) | L3MBTL1MAPTKDM4EHPGDHTT | |
| SCHEMBL22366449 | 0.76 | L3MBTL1 (0.47) | L3MBTL1KDM4EHPGDHSD17B10ACHE | |
| SCHEMBL11962909 | 0.75 | MAPT (0.44) | L3MBTL1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL8507123 | 0.75 | HPGD (0.67) | L3MBTL1MAPTHPGDHSD17B10RAB9A | |
| SCHEMBL31717077 | 0.75 | LMNA (0.46) | L3MBTL1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL30890579 | 0.74 | HPGD (0.65) | MAPTHPGDHSD17B10RAB9AKMT2A | |
| SCHEMBL30097038 | 0.74 | L3MBTL1 (0.38) | L3MBTL1ACHERAB9ATGFBR1 | |
| SCHEMBL30097047 | 0.74 | FAAH (0.44) | L3MBTL1MAPTHPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015121660-A1 | PYRAZOLYL-UREAS AS KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2015-08-20 | — | — | WO | disclosed |