SCHEMBL30100935

SCHEMBL30100935

C=C(c1ccc(N(CC)CC)cc1)c1ccc([SiH](C)C)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
CYP3A4 P08684 2/20 0.41
MAPK1 P28482 2/20 0.41
RECQL P46063 2/20 0.41
TSHR P16473 2/20 0.41
PSMD14 O00487 1/20 0.41
GFER P55789 1/20 0.41
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
MAPT P10636 5/20 0.41
GAA P10253 3/20 0.41
POLB P06746 3/20 0.41
NOX1 Q9Y5S8 2/20 0.41
MCL1 Q07820 1/20 0.41
ALDH3A1 P30838 1/20 0.39
ALDH1A3 P47895 1/20 0.39
HSP90AA1 P07900 2/20 0.39
NSD2 O96028 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1458445 0.87 ALDH1A1 (0.52) ALDH1A1L3MBTL1TDP1CYP3A4MAPK1
SCHEMBL8905273 0.85 ALDH1A1 (0.54) ALDH1A1L3MBTL1TDP1CYP3A4MAPK1
SCHEMBL609137 0.80 MEN1 (0.63) ALDH1A1L3MBTL1TDP1CYP3A4MAPK1
SCHEMBL10603474 0.80 MEN1 (0.63) ALDH1A1L3MBTL1TDP1CYP3A4MAPK1
SCHEMBL17811534 0.77 ALDH1A1 (0.50) ALDH1A1L3MBTL1TDP1CYP3A4MAPK1
SCHEMBL9502935 0.76 MAPT (0.49) ALDH1A1L3MBTL1TDP1CYP3A4MAPK1
SCHEMBL10472828 0.75 POLB (0.49) ALDH1A1L3MBTL1MAPK1TSHRKMT2A
SCHEMBL10473325 0.74 MEN1 (0.42) ALDH1A1L3MBTL1TDP1CYP3A4MAPK1
SCHEMBL28309937 0.74 MEN1 (0.53) TSHRGFERMEN1KMT2AMAPT
SCHEMBL611731 0.74 MAPT (0.51) ALDH1A1L3MBTL1TDP1CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115536762-B Liquid crystal grafted modified polystyrene with wide liquid crystal temperature range, differential photoresponse and reversible isomerization and preparation method thereof 大连理工大学 2024-06-14 CN claimed
CN-115536762-A Differential photoresponse and isomerization reversible liquid crystal grafted modified polystyrene with wide liquid crystal temperature domain and preparation method thereof 大连理工大学 2022-12-30 CN claimed
CN-115536762-B Liquid crystal grafted modified polystyrene with wide liquid crystal temperature range, differential photoresponse and reversible isomerization and preparation method thereof 大连理工大学 2024-06-14 CN disclosed
CN-115536762-A Differential photoresponse and isomerization reversible liquid crystal grafted modified polystyrene with wide liquid crystal temperature domain and preparation method thereof 大连理工大学 2022-12-30 CN disclosed