Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.45 |
| ▸ | IL1B | P01584 | 5/20 | 0.36 |
| ▸ | TNF | P01375 | 2/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30517825 | 0.86 | NLRP3 (0.47) | NLRP3IL1BTNFMAPK8 | |
| SCHEMBL30101125 | 0.73 | KAT2B (0.42) | NLRP3IL1B | |
| SCHEMBL30101082 | 0.73 | KAT2B (0.42) | NLRP3IL1B | |
| SCHEMBL28934678 | 0.72 | NLRP3 (0.51) | NLRP3IL1BTNF | |
| SCHEMBL30108846 | 0.72 | NLRP3 (0.51) | NLRP3IL1BTNF | |
| SCHEMBL25857019 | 0.72 | NLRP3 (0.51) | NLRP3IL1BTNF | |
| SCHEMBL30101077 | 0.72 | EHMT2 (0.38) | IL1B | |
| SCHEMBL30517850 | 0.67 | IL1B (0.45) | NLRP3IL1BTNF | |
| SCHEMBL25854947 | 0.65 | NLRP3 (0.62) | NLRP3IL1BTNF | |
| SCHEMBL25855651 | 0.65 | NLRP3 (0.57) | NLRP3IL1BTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |
| WO-2022253326-A1 | NLRP3 INFLAMMASOME INHIBITOR AND APPLICATION THEREOF | 药捷安康(南京)科技股份有限公司 | 2022-12-08 | — | — | WO | disclosed |