Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 9/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.42 |
| ▸ | BPTF | Q12830 | 1/20 | 0.41 |
| ▸ | IL1B | P01584 | 5/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30101125 | 1.00 | KAT2B (0.42) | KAT2BEHMT2BPTFIL1BNLRP3 | |
| SCHEMBL30101069 | 0.88 | KAT2B (0.44) | KAT2BEHMT2BPTFIL1BNLRP3 | |
| SCHEMBL30040847 | 0.74 | KAT2B (0.44) | KAT2BEHMT2BPTFIL1BNLRP3 | |
| SCHEMBL24574835 | 0.74 | KAT2B (0.44) | KAT2BEHMT2BPTFIL1BNLRP3 | |
| SCHEMBL30101077 | 0.74 | EHMT2 (0.38) | EHMT2IL1B | |
| SCHEMBL30156973 | 0.74 | NLRP3 (0.45) | KAT2BEHMT2BPTFIL1BNLRP3 | |
| SCHEMBL29276058 | 0.73 | KAT2B (0.44) | KAT2BEHMT2BPTFIL1BNLRP3 | |
| SCHEMBL29276062 | 0.73 | KAT2B (0.44) | KAT2BEHMT2BPTFIL1BNLRP3 | |
| SCHEMBL30101023 | 0.73 | NLRP3 (0.45) | IL1BNLRP3 | |
| SCHEMBL25297092 | 0.73 | IL1B (0.51) | KAT2BBPTFIL1BNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253326-A1 | NLRP3 INFLAMMASOME INHIBITOR AND APPLICATION THEREOF | 药捷安康(南京)科技股份有限公司 | 2022-12-08 | — | — | WO | disclosed |