SCHEMBL30101077 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	EHMT2	Q96KQ7	6/20	0.38

▸	BRD4	O60885	1/20	0.38

▸	CHEK2	O96017	3/20	0.37

▸	IL1B	P01584	1/20	0.37

▸	PRKCI	P41743	3/20	0.35

▸	RPS6KB1	P23443	3/20	0.34

▸	AURKA	O14965	2/20	0.34

▸	CHEK1	O14757	2/20	0.34

▸	PRKCZ	Q05513	1/20	0.34

▸	PDPK1	O15530	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30101125	0.74	KAT2B (0.42)	EHMT2IL1B
SCHEMBL30101082	0.74	KAT2B (0.42)	EHMT2IL1B
SCHEMBL30101112	0.74	PRKCI (0.40)	EHMT2BRD4CHEK2IL1BPRKCI
SCHEMBL30108831	0.72	PRKCI (0.40)	EHMT2BRD4CHEK2IL1BPRKCI
SCHEMBL30108649	0.72	PRKCI (0.40)	EHMT2BRD4CHEK2IL1BPRKCI
SCHEMBL30101023	0.72	NLRP3 (0.45)	IL1B
Hydrochloric Acid SCHEMBL31367806	0.67	BRD4 (0.44)	EHMT2BRD4CHEK2IL1BCHEK1
SCHEMBL31021521	0.63	IL1B (0.55)	EHMT2BRD4CHEK2IL1BPRKCI
SCHEMBL30259588	0.63	KDM4E (0.61)	BRD4PRKCZ
SCHEMBL31367809	0.62	CHEK1 (0.45)	IL1BCHEK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022253326-A1	NLRP3 INFLAMMASOME INHIBITOR AND APPLICATION THEREOF	药捷安康(南京)科技股份有限公司	2022-12-08	—	—	WO	disclosed