SCHEMBL30101113

SCHEMBL30101113

Cc1cc(C#N)ccc1B1OC(C)(C)C(C)(C)O1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.35
ALDH1A1 P00352 1/20 0.35
ESR2 Q92731 1/20 0.33
PDE4B Q07343 2/20 0.33
MALT1 Q9UDY8 1/20 0.33
CHRM1 P11229 1/20 0.32
PDE4A P27815 1/20 0.32
ADRA1A P35348 1/20 0.32
PDE1A P54750 1/20 0.32
PDE4C Q08493 1/20 0.32
PDE4D Q08499 1/20 0.32
PDE3B Q13370 1/20 0.32
PDE7A Q13946 1/20 0.32
PDE3A Q14432 1/20 0.32
AR P10275 3/20 0.32
LPL P06858 4/20 0.32
LIPG Q9Y5X9 4/20 0.32
ABCB1 P08183 1/20 0.31
EGLN2 Q96KS0 3/20 0.31
CYP11B1 P15538 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL931715 1.00 CYP2A6 (0.35) CYP2A6ALDH1A1ESR2PDE4BMALT1
SCHEMBL14895853 0.87 CYP2A6 (0.35) CYP2A6ALDH1A1ESR2PDE4BMALT1
SCHEMBL23076675 0.85 MAOA (0.42) CYP2A6ALDH1A1PDE4BCHRM1PDE4A
SCHEMBL23030124 0.84 PDE4B (0.49) PDE4BCHRM1PDE4AADRA1APDE1A
SCHEMBL31058250 0.82 AR (0.37) CYP2A6ESR2PDE4BCHRM1PDE4A
SCHEMBL29358185 0.82 CYP11B2 (0.38) CYP2A6ALDH1A1ESR2PDE4BCHRM1
SCHEMBL30372881 0.82 ALDH1A1 (0.36) CYP2A6ALDH1A1ESR2PDE4BCHRM1
SCHEMBL156525 0.82 CYP11B2 (0.38) CYP2A6ALDH1A1ESR2PDE4BCHRM1
SCHEMBL22637023 0.82 ALDH1A1 (0.36) CYP2A6ALDH1A1ESR2PDE4BCHRM1
SCHEMBL10041745 0.82 AR (0.37) CYP2A6ESR2PDE4BCHRM1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025129135-A2 COMPOSITIONS COMPRISING USP1 INHIBITORS AND METHODS OF USING THE SAME EIKON THERAPEUTICS, INC. (US) 2025-06-19 WO disclosed
WO-2025129076-A1 PYRIDOPYRIMIDINE AND QUINAZOLINE DERIVATIVES AS USP1 INHIBITORS, COMPOSITIONS COMPRISING THEM AND METHODS OF USING THE SAME EIKON THERAPEUTICS, INC. (US) 2025-06-19 WO disclosed
EP-4463456-A1 THIAZOLOPYRIDYL AMIDE DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS BeiGene, Ltd. (KY) 2024-11-20 EP disclosed
WO-2023134708-A1 THIAZOLOPYRIDYL AMIDE DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS BEIGENE , LTD. (KY) 2023-07-20 WO disclosed
WO-2022253326-A1 NLRP3 INFLAMMASOME INHIBITOR AND APPLICATION THEREOF 药捷安康(南京)科技股份有限公司 2022-12-08 WO disclosed