Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 3/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725118 | 0.77 | POLB (0.40) | CYP1A2CYP2D6ALDH1A1POLBCA1 | |
| SCHEMBL4246548 | 0.72 | ALDH1A1 (0.37) | CYP1A2ALDH1A1MAPTSIGMAR1THRB | |
| Fluoride SCHEMBL1963693 | 0.71 | HRH3 (0.52) | CYP1A2ALDH1A1MAPTPOLBSIGMAR1 | |
| SCHEMBL16625898 | 0.70 | POLB (0.41) | ALDH1A1MAPTPOLBSIGMAR1THRB | |
| SCHEMBL12883403 | 0.69 | CA1 (0.64) | ALDH1A1CA1CA9LMNATSHR | |
| SCHEMBL23600074 | 0.69 | HRH3 (0.55) | CYP1A2ALDH1A1MAPTPOLBSIGMAR1 | |
| SCHEMBL2745438 | 0.69 | — | — | |
| SCHEMBL19250122 | 0.69 | HRH3 (0.55) | CYP1A2ALDH1A1MAPTPOLBSIGMAR1 | |
| SCHEMBL14926143 | 0.69 | HRH3 (0.55) | CYP1A2ALDH1A1MAPTPOLBSIGMAR1 | |
| SCHEMBL81143 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4358970-A1 | COMPOUNDS FOR TREATING GENETIC DISEASES | Zikani Therapeutics, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022251730-A1 | COMPOUNDS FOR TREATING GENETIC DISEASES | ZIKANI THERAPEUTICS, INC. (US) | 2022-12-01 | — | — | WO | disclosed |