Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4246548 | 0.82 | ALDH1A1 (0.37) | ALDH1A1LMNATHRBL3MBTL1PKM | |
| SCHEMBL16271545 | 0.80 | CARM1 (0.47) | POLB | |
| SCHEMBL30101299 | 0.77 | TERT (0.33) | POLBALDH1A1LMNATSHRTHRB | |
| SCHEMBL1180845 | 0.74 | POLB (0.46) | POLBALDH1A1THRBL3MBTL1NPC1 | |
| SCHEMBL8114400 | 0.74 | POLB (0.46) | POLBALDH1A1THRBL3MBTL1NPC1 | |
| Ethylene SCHEMBL10739489 | 0.73 | ALDH1A1 (0.41) | POLBALDH1A1LMNATSHRTHRB | |
| Iodide SCHEMBL1514951 | 0.73 | POLB (0.45) | POLBALDH1A1THRBL3MBTL1NPC1 | |
| Hydrochloric Acid SCHEMBL3727010 | 0.73 | POLB (0.45) | POLBALDH1A1THRBL3MBTL1NPC1 | |
| SCHEMBL13309991 | 0.73 | — | — | |
| Bromide SCHEMBL3742304 | 0.73 | POLB (0.45) | POLBALDH1A1THRBL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9163114-B2 | Biodegradable shape memory polymer | UNIVERSITY OF MASSACHUSETTS (US) | 2015-10-20 | — | — | US | disclosed |
| US-9163114-B2 | Biodegradable shape memory polymer | UNIVERSITY OF MASSACHUSETTS (US) | 2015-10-20 | — | — | US | disclosed |
| US-20130150533-A1 | BIODEGRADABLE SHAPE MEMORY POLYMER | UNIVERSITY OF MASSACHUSETTS | 2013-06-13 | — | — | US | disclosed |
| US-20130150533-A1 | BIODEGRADABLE SHAPE MEMORY POLYMER | UNIVERSITY OF MASSACHUSETTS | 2013-06-13 | — | — | US | disclosed |
| WO-2012027573-A2 | BIODEGRADABLE SHAPE MEMORY POLYMER | UNIVERSITY OF MASSACHUSETTS (US) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012027573-A2 | BIODEGRADABLE SHAPE MEMORY POLYMER | UNIVERSITY OF MASSACHUSETTS (US) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150533-A1 | BIODEGRADABLE SHAPE MEMORY POLYMER | TLR1, SMC1A, PUF60 | POLB 2793/4885ALDH1A1 2762/4885LMNA 3174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.