SCHEMBL3010135

SCHEMBL3010135

CCOC(=O)c1c(C)sc(-c2cc(CN3CCN(Cc4cc(-c5sc(C)c(C(=O)OCC)c5C)cc(C(=O)OC)n4)CCN(Cc4cc(-c5sc(C)c(C(=O)OCC)c5C)cc(C(=O)OC)n4)CC3)nc(C(=O)OC)c2)c1C

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.41
TP53 P04637 3/20 0.41
RXFP1 Q9HBX9 1/20 0.38
GRM6 O15303 5/20 0.38
ALDH1A1 P00352 4/20 0.37
GAA P10253 1/20 0.37
HPGD P15428 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.36
ACKR3 P25106 1/20 0.35
TSHR P16473 1/20 0.35
RECQL P46063 1/20 0.35
THRB P10828 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3691760 0.80 MAPT (0.37) MAPTTP53ALDH1A1GAAMEN1
SCHEMBL3020892 0.74 LMNA (0.40) MAPTTP53ALDH1A1GAAHPGD
SCHEMBL3693210 0.73 CHRM2 (0.39) MAPTTP53RXFP1ALDH1A1MEN1
SCHEMBL13214426 0.73 TP53 (0.33) MAPTTP53ALDH1A1TSHR
SCHEMBL842177 0.73 ALDH1A1 (0.41) TP53ALDH1A1GAAHPGDNPSR1
SCHEMBL3021173 0.73 ALDH1A1 (0.38) MAPTTP53ALDH1A1HPGDNPSR1
SCHEMBL13234553 0.72 ALDH1A1 (0.35) MAPTTP53RXFP1ALDH1A1HPGD
SCHEMBL862555 0.72 CYP1A2 (0.44) MAPTRXFP1ALDH1A1GAAHPGD
SCHEMBL17481796 0.71 ALDH1A1 (0.48) MAPTALDH1A1HPGDLMNA
SCHEMBL13214432 0.70 MAPT (0.35) MAPTTP53ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2195310-B1 LUMINESCENT LANTHANIDE (III) CHELATES, CHELATING AGENTS AND CONJUGATES DERIVED THEREOF WALLAC OY (FI) 2016-06-01 EP disclosed
US-8221719-B2 Luminescent lanthanide (III) chelates, chelating agents and conjugates derived thereof WALLAC OY (FI) 2012-07-17 US disclosed
US-20100204442-A1 Luminescent lanthanide (III) chelates, chelating agents and conjugates derived thereof WALLAC OY (FI) 2010-08-12 US disclosed
EP-2195310-A1 LUMINESCENT LANTHANIDE (III) CHELATES, CHELATING AGENTS AND CONJUGATES DERIVED THEREOF Wallac OY (FI) 2010-06-16 EP disclosed
WO-2009030819-A1 LUMINESCENT LANTHANIDE (III) CHELATES, CHELATING AGENTS AND CONJUGATES DERIVED THEREOF WALLAC OY (FI) 2009-03-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204442-A1 Luminescent lanthanide (III) chelates, chelating agents and conjugates derived thereof LNPEP, SLC39A3, LAP3 MAPT 2629/4885TP53 1354/4885RXFP1 923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.