Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 2/20 | 0.35 |
| ▸ | TNKS | O95271 | 3/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30101920 | 0.84 | PIM1 (0.38) | PTGS2PTGS1PIM1NPY5RPIM2 | |
| SCHEMBL31472806 | 0.83 | XDH (0.41) | PIM1MAPTL3MBTL1 | |
| SCHEMBL30101960 | 0.81 | PIM1 (0.37) | PTGS2PTGS1PIM1NPY5RPIM2 | |
| SCHEMBL31472805 | 0.80 | PIM1 (0.39) | PTGS2PTGS1PIM1NPY5RDGAT1 | |
| SCHEMBL30101909 | 0.79 | AHR (0.39) | PTGS2PTGS1PIM1NPY5RDGAT1 | |
| SCHEMBL30101887 | 0.79 | PIM1 (0.39) | PTGS2PTGS1PIM1NPY5RDGAT1 | |
| SCHEMBL23950293 | 0.78 | PTGS2 (0.42) | PTGS2PTGS1TRPV1PIM1NPY5R | |
| SCHEMBL31472804 | 0.78 | PIM1 (0.37) | PTGS2PTGS1PIM1NPY5RDGAT1 | |
| SCHEMBL30101858 | 0.78 | AHR (0.38) | PTGS2PTGS1PIM1NPY5RDGAT1 | |
| SCHEMBL30101972 | 0.76 | TNKS (0.50) | PIM1NPY5RDGAT1KCNH2KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115443276-A | Pyridopyrimidinone derivatives and their use as modulators of aromatic hydrocarbon receptors | 东亚ST株式会社 | 2022-12-06 | — | — | CN | claimed |
| CN-115443276-B | Pyridopyrimidinone derivatives and their use as arene receptor modulators | 东亚ST株式会社 | 2025-04-18 | — | — | CN | disclosed |
| CN-115443276-A | Pyridopyrimidinone derivatives and their use as modulators of aromatic hydrocarbon receptors | 东亚ST株式会社 | 2022-12-06 | — | — | CN | disclosed |