Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | YES1 | P07947 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3010179 | 0.90 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2PLA2G2AMEN1 | |
| SCHEMBL3001953 | 0.89 | PLA2G2A (0.58) | PLA2G2AMEN1KMT2AMAPTPTGS2 | |
| SCHEMBL2995989 | 0.87 | PLA2G2A (0.48) | RAB9ANPC1PLA2G2AALOX5MEN1 | |
| SCHEMBL4090109 | 0.84 | FAAH (0.61) | RAB9ANPC1FAAHMEN1KMT2A | |
| SCHEMBL8805925 | 0.79 | MAPT (0.54) | RAB9ANPC1PLA2G2APTGESALOX5 | |
| SCHEMBL16222850 | 0.77 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2PLA2G2AMEN1 | |
| SCHEMBL3003091 | 0.76 | FAAH (0.58) | FAAHMEN1KMT2AKDM4EHPGD | |
| SCHEMBL4096106 | 0.76 | FAAH (0.51) | RAB9ANPC1FAAHMEN1KMT2A | |
| SCHEMBL8804947 | 0.75 | KDM4E (0.54) | RAB9ASMN1; SMN2PLA2G2AMEN1KMT2A | |
| SCHEMBL16222857 | 0.74 | PLA2G2A (0.50) | RAB9ANPC1PLA2G2AALOX5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197708-A1 | INDOLE COMPOUNDS | WELLS FARGO BANK, NATIONAL ASSOCIATION | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197708-A1 | INDOLE COMPOUNDS | IDO1, IDO2, TPH2 | RAB9A 3562/4885NPC1 2681/4885SMN1; SMN2 3581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.