Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.40 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.40 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24785096 | 1.00 | KMT2A (0.47) | KMT2ANR1H2NR1H3CCR2EGLN1 | |
| SCHEMBL24785074 | 0.92 | NR1H2 (0.42) | KMT2ANR1H2NR1H3METLMNA | |
| SCHEMBL30103084 | 0.92 | NR1H2 (0.42) | KMT2ANR1H2NR1H3METLMNA | |
| SCHEMBL30103058 | 0.90 | NPBWR1 (0.41) | KMT2ACCR2EGLN1 | |
| SCHEMBL24784545 | 0.90 | NPBWR1 (0.41) | KMT2ACCR2EGLN1 | |
| SCHEMBL24785451 | 0.87 | MEN1 (0.43) | KMT2ANR1H2NR1H3EGLN1LMNA | |
| SCHEMBL30018739 | 0.87 | MEN1 (0.43) | KMT2ANR1H2NR1H3EGLN1LMNA | |
| SCHEMBL24784619 | 0.86 | P2RX7 (0.38) | KMT2ANR1H2NR1H3METPPARG | |
| SCHEMBL30103035 | 0.86 | P2RX7 (0.38) | KMT2ANR1H2NR1H3METPPARG | |
| SCHEMBL24784641 | 0.85 | MDM2 (0.36) | KMT2AEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |