SCHEMBL30103346

SCHEMBL30103346

CC(=Cc1cccc(C(C)(C)C)c1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.59
MPL P40238 1/20 0.47
TBXAS1 P24557 2/20 0.44
SLC9A1 P19634 1/20 0.44
SLC9A3 P48764 1/20 0.44
SLC9A2 Q9UBY0 1/20 0.44
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
ACHE P22303 3/20 0.42
HDAC4 P56524 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
CYP26B1 Q9NR63 2/20 0.40
CYP26A1 O43174 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
HTT P42858 1/20 0.39
TRPV1 Q8NER1 1/20 0.39
NOTUM Q6P988 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8042956 0.85 AKR1C3 (0.58) AKR1C3LMNAMAPTHPGDHTT
SCHEMBL5004361 0.85 AKR1C3 (0.58) AKR1C3LMNAMAPTHPGDHTT
SCHEMBL8746676 0.84 AKR1C3 (0.76) AKR1C3MPLTBXAS1SLC9A1SLC9A3
SCHEMBL8746678 0.84 AKR1C3 (0.76) AKR1C3MPLTBXAS1SLC9A1SLC9A3
SCHEMBL9636925 0.80 HDAC8 (0.44) SLC9A1SLC9A3SLC9A2RXRARXRB
SCHEMBL2005648 0.79 AKR1C3 (0.62) AKR1C3MPLTBXAS1MAPTHPGD
SCHEMBL2005650 0.79 AKR1C3 (0.62) AKR1C3MPLTBXAS1MAPTHPGD
SCHEMBL10427712 0.78 ALDH1A1 (0.56) SLC9A1SLC9A3SLC9A2RXRARXRB
SCHEMBL799992 0.78 ALDH1A1 (0.56) SLC9A1SLC9A3SLC9A2RXRARXRB
SCHEMBL2419606 0.77 AKR1C3 (0.66) AKR1C3TBXAS1SLC9A1SLC9A3SLC9A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111253236-B Preparation method of high-quality para-lilial 宿迁科思化学有限公司 2022-11-18 CN disclosed