SCHEMBL799992

SCHEMBL799992

C/C(C=O)=C\c1cccc(C(C)(C)C)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
TSHR P16473 1/20 0.56
HDAC8 Q9BY41 2/20 0.43
HDAC4 P56524 1/20 0.43
HDAC2 Q92769 1/20 0.43
ACHE P22303 3/20 0.40
TRPV1 Q8NER1 1/20 0.40
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
CYP26B1 Q9NR63 4/20 0.38
CYP26A1 O43174 2/20 0.38
THRB P10828 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
CYP1A2 P05177 1/20 0.36
KIF11 P52732 1/20 0.35
SLC9A1 P19634 1/20 0.35
SLC9A3 P48764 1/20 0.35
SLC9A2 Q9UBY0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10427712 1.00 ALDH1A1 (0.56) ALDH1A1TSHRHDAC8HDAC4HDAC2
SCHEMBL28108410 0.85 ALDH1A1 (0.55) ALDH1A1TSHRTHRBL3MBTL1MAOA
SCHEMBL9636925 0.82 HDAC8 (0.44) ALDH1A1HDAC8HDAC4HDAC2ACHE
SCHEMBL119154 0.78 ALDH1A1 (0.59) ALDH1A1TSHRTRPV1CYP1A2
SCHEMBL119153 0.78 ALDH1A1 (0.59) ALDH1A1TSHRTRPV1CYP1A2
SCHEMBL30103346 0.78 AKR1C3 (0.59) HDAC8HDAC4HDAC2ACHETRPV1
SCHEMBL29846591 0.77 ALDH1A1 (0.48) ALDH1A1HDAC8HDAC4HDAC2ACHE
SCHEMBL309484 0.77 ALDH1A1 (0.48) ALDH1A1HDAC8HDAC4HDAC2ACHE
SCHEMBL3222257 0.77 ALDH1A1 (0.62) ALDH1A1TSHRACHEMAOAMAOB
SCHEMBL10410990 0.77 ALDH1A1 (0.62) ALDH1A1TSHRACHEMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2238097-A None JP disclosed
EP-2616424-B1 METHOD FOR PRODUCING 2-METHYL-3-(4-TERT-BUTYLPHENYL)-PROPANAL HAVING HIGH PARA-ISOMER PURITY BASF SE (DE) 2015-08-26 EP disclosed
US-20120071696-A1 PROCESS FOR PREPARING 2-METHYL-3-(4-TERT-BUTYLPHENYL)PROPANAL WITH HIGH PARA-ISOMER PURITY BASF SE (DE) 2012-03-22 US disclosed
US-20120071696-A1 PROCESS FOR PREPARING 2-METHYL-3-(4-TERT-BUTYLPHENYL)PROPANAL WITH HIGH PARA-ISOMER PURITY BASF SE (DE) 2012-03-22 US disclosed
WO-2012034930-A1 METHOD FOR PRODUCING 2-METHYL-3-(4-TERT-BUTYLPHENYL)-PROPANAL HAVING HIGH PARA-ISOMER PURITY BASF SE (DE) 2012-03-22 WO disclosed
JP-H02238097-A PERFUME COMPOSITION KURARAY CO LTD 1990-09-20 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071696-A1 PROCESS FOR PREPARING 2-METHYL-3-(4-TERT-BUTYLPHENYL)PROPANAL WITH HIGH PARA-ISOMER PURITY HPD, PAH, PTMA ALDH1A1 97/4885TSHR 2594/4885HDAC8 4112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.