Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | P4HB | P07237 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5004361 | 1.00 | AKR1C3 (0.58) | AKR1C3LMNAMAPTHPGDTHRB | |
| SCHEMBL30103346 | 0.85 | AKR1C3 (0.59) | AKR1C3LMNAMAPTHPGDHTT | |
| SCHEMBL10747237 | 0.84 | THRB (0.47) | LMNAMAPTHPGDTHRBL3MBTL1 | |
| SCHEMBL9478264 | 0.84 | THRB (0.47) | LMNAMAPTHPGDTHRBL3MBTL1 | |
| SCHEMBL9478271 | 0.84 | THRB (0.47) | LMNAMAPTHPGDTHRBL3MBTL1 | |
| SCHEMBL5381429 | 0.83 | MAOB (0.51) | LMNAMAPTMAOBNFE2L2MEN1 | |
| SCHEMBL8746678 | 0.82 | AKR1C3 (0.76) | AKR1C3MEN1KMT2AHTTKDM4E | |
| SCHEMBL8746676 | 0.82 | AKR1C3 (0.76) | AKR1C3MEN1KMT2AHTTKDM4E | |
| SCHEMBL11865025 | 0.82 | GLO1 (0.53) | LMNAMAPTHPGDTHRBL3MBTL1 | |
| SCHEMBL700921 | 0.82 | MAOB (0.50) | LMNAMAPTMAOBNFE2L2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025349-A | ANTIARRHYTHMIC PROPERTIES, | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-02-15 | — | — | US | disclosed |