Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.39 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1554030 | 0.82 | SLC9A1 (0.48) | SLC9A1SLC9A3SLC9A2ALDH1A1TDP1 | |
| SCHEMBL799992 | 0.82 | ALDH1A1 (0.56) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL10427712 | 0.82 | ALDH1A1 (0.56) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL30103346 | 0.80 | AKR1C3 (0.59) | HDAC8HDAC4HDAC2ACHESLC9A1 | |
| SCHEMBL16952172 | 0.79 | HDAC8 (0.47) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL5433181 | 0.79 | HDAC8 (0.45) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL349422 | 0.77 | HDAC8 (0.44) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL781852 | 0.77 | HDAC8 (0.44) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL30277113 | 0.75 | TDP1 (0.54) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL18302082 | 0.75 | HDAC8 (0.47) | HDAC8HDAC4HDAC2ACHEKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0294557-B1 | PROCESS FOR THE PREPARATION OF 3-PHENYL-2-METHYLPROPANOL AND ITS PARA-SUBSTITUTED ALKYLIC DERIVATIVES | HÜLS AKTIENGESELLSCHAFT (DE) | 1992-07-08 | — | — | EP | disclosed |
| EP-0294557-A2 | Process for the preparation of 3-phenyl-2-methylpropanol and its para-substituted alkylic derivatives | HÜLS AKTIENGESELLSCHAFT (DE) | 1988-12-14 | — | — | EP | disclosed |