SCHEMBL30103963

SCHEMBL30103963

c1ccc2c(c1)[nH]c1ccc3cncnc3c12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 2/20 0.59
CCND1 P24385 2/20 0.59
GABRA1 P14867 8/20 0.46
GABRG2 P18507 8/20 0.46
GABRB3 P28472 8/20 0.46
GABRA3 P34903 8/20 0.46
GABRA2 P47869 8/20 0.46
GABRA5 P31644 7/20 0.46
GABRP O00591 5/20 0.46
GABRD O14764 5/20 0.46
GABRB1 P18505 5/20 0.46
GABRB2 P47870 5/20 0.46
GABRA4 P48169 5/20 0.46
GABRE P78334 5/20 0.46
GABRA6 Q16445 5/20 0.46
GABRG1 Q8N1C3 5/20 0.46
GABRG3 Q99928 5/20 0.46
GABRQ Q9UN88 5/20 0.46
ACHE P22303 1/20 0.41
IMPDH2 P12268 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1458276 1.00 CDK4 (0.59) CDK4CCND1GABRA1GABRG2GABRB3
SCHEMBL29946446 0.79 CDK4 (0.55) CDK4CCND1GABRA1GABRG2GABRB3
SCHEMBL542799 0.79 CDK4 (0.55) CDK4CCND1GABRA1GABRG2GABRB3
Benzene SCHEMBL29042456 0.78 CDK4 (0.54) CDK4CCND1GABRA1GABRG2GABRB3
SCHEMBL21398149 0.77 CDK4 (0.43) CDK4CCND1GABRA1GABRG2GABRB3
SCHEMBL2391060 0.76 GABRA1 (0.53) GABRA1GABRG2GABRB3GABRA3GABRA2
SCHEMBL30320037 0.76 GABRA1 (0.53) GABRA1GABRG2GABRB3GABRA3GABRA2
SCHEMBL8134425 0.76 CDK4 (0.53) CDK4CCND1GABRA1GABRG2GABRB3
SCHEMBL2461988 0.76 CDK4 (0.53) CDK4CCND1GABRA1GABRG2GABRB3
SCHEMBL21398086 0.75 CDK4 (0.42) CDK4CCND1GABRA1GABRG2GABRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112745322-B Organic material and application thereof in organic electroluminescent device 北京燕化集联光电技术有限公司 2022-12-02 CN disclosed
CN-112745321-B Compound containing indoloquinazolinedione structure and application thereof 北京燕化集联光电技术有限公司 2022-12-02 CN disclosed