SCHEMBL2391060

SCHEMBL2391060

c1ccc2c(c1)[nH]c1cncnc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.53
GABRG2 P18507 4/20 0.53
GABRB3 P28472 4/20 0.53
GABRA5 P31644 4/20 0.53
GABRA3 P34903 4/20 0.53
GABRA2 P47869 4/20 0.53
GABRP O00591 3/20 0.53
GABRD O14764 3/20 0.53
GABRB1 P18505 3/20 0.53
GABRB2 P47870 3/20 0.53
GABRA4 P48169 3/20 0.53
GABRE P78334 3/20 0.53
GABRA6 Q16445 3/20 0.53
GABRG1 Q8N1C3 3/20 0.53
GABRG3 Q99928 3/20 0.53
GABRQ Q9UN88 3/20 0.53
ALDH1A1 P00352 3/20 0.53
KDM4E B2RXH2 3/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
IKBKB O14920 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30320037 1.00 GABRA1 (0.53) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL12590234 0.81 CHUK (0.53) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL12590229 0.79 ACHE (0.52) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL12396543 0.79 MAPK14 (0.42) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL12590228 0.77 GABRA1 (0.47) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL1849463 0.77 MAPT (0.49) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL1458276 0.76 CDK4 (0.59) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL30103963 0.76 CDK4 (0.59) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL2628321 0.75 GABRP (0.49) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL2628327 0.75 KDM4E (0.55) GABRA1GABRG2GABRB3GABRA5GABRA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 434 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559671-B2 Light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2026-02-24 US claimed
US-12457894-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2025-10-28 US claimed
US-20250257089-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2025-08-14 US claimed
US-12324349-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2025-06-03 US claimed
US-12289985-B2 Organic light-emitting device, apparatus including the same, and organometallic compound SAMSUNG DISPLAY CO., LTD. (KR) 2025-04-29 US claimed
CN-110943185-B Organic light-emitting device, apparatus including the same, and organometallic compound 三星显示有限公司 2025-01-03 CN claimed
EP-3882253-B1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2024-11-27 EP claimed
US-12144243-B2 Organometallic compound, light-emitting device including same, and electronic apparatus including the light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2024-11-12 US claimed
US-12108655-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2024-10-01 US claimed
US-12101996-B2 Organometallic compound, light-emitting device including the same, and electronic apparatus SAMSUNG DISPLAY CO., LTD. (KR) 2024-09-24 US claimed
US-20160351817-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-12-01 US claimed
EP-3098873-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2016-11-30 EP claimed
US-20160293863-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-10-06 US claimed
EP-2104675-A1 SUBSTITUTED 5H-PYRIMIDOL[5,4-B]INDOLES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF FOR TREATING NON-SOLID MALIGNANT TUMORS OF THE BLOOD-PRODUCING SYSTEM The Medicines Company (Leipzig) GmbH (DE) 2009-09-30 EP claimed
WO-2008077631-A1 SUBSTITUTED 5H-PYRIMIDOL[5,4-B]INDOLES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF FOR TREATING NON-SOLID MALIGNANT TUMORS OF THE BLOOD-PRODUCING SYSTEM THE MEDICINES COMPANY (LEIPZIG) GMBH (DE) 2008-07-03 WO claimed
EP-0552237-A1 CERTAIN CYCLOALKYL AND AZACYCLOALKYL PYRROLOPYRIMIDINES; A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS NEUROGEN CORPORATION (US) 1993-07-28 EP claimed
WO-1992006094-A1 CERTAIN CYCLOALKYL AND AZACYCLOALKYL PYRROLOPYRIMIDINES; A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS NEUROGEN CORPORATION (US) 1992-04-16 WO claimed
EP-0115248-B1 SUBSTITUTED 5H-PYRIMIDO(5,4-B)INDOLES SCHERING AKTIENGESELLSCHAFT (DE) 1990-02-28 EP claimed
US-4564610-A Substituted 5H-pyrimido[5,4-b]indoles SCHERING AKTIENGESELLSCHAFT (DE) 1986-01-14 US claimed
EP-0115248-A1 Substituted 5H-pyrimido(5,4-b)indoles SCHERING AKTIENGESELLSCHAFT (DE) 1984-08-08 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160293863-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device IDO1, INTS6, AHR GABRA1 2332/4885GABRG2 3111/4885GABRB3 2709/4885
US-12101996-B2 Organometallic compound, light-emitting device including the same, and electronic apparatus CRY1, LAGE3, LEF1 GABRA1 2438/4885GABRG2 2838/4885GABRB3 3972/4885
US-12289985-B2 Organic light-emitting device, apparatus including the same, and organometallic compound LEF1, OCIAD1, OXA1L GABRA1 2632/4885GABRG2 3386/4885GABRB3 4076/4885
US-12108655-B2 Organometallic compound and organic light-emitting device including the same LEF1, CRY1, ODC1 GABRA1 1782/4885GABRG2 2558/4885GABRB3 3424/4885
US-12144243-B2 Organometallic compound, light-emitting device including same, and electronic apparatus including the light-emitting device GPX1, LAGE3, NFE2L2 GABRA1 3182/4885GABRG2 3222/4885GABRB3 4059/4885
US-12457894-B2 Organometallic compound and organic light-emitting device including the same CRY1, OCIAD1, ORC3 GABRA1 2398/4885GABRG2 3000/4885GABRB3 3773/4885
US-12559671-B2 Light-emitting device SCO2, GRIN2C, GLRA2 GABRA1 2763/4885GABRG2 2619/4885GABRB3 2789/4885
US-20250257089-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME MT-CO1, OXA1L, CRY1 GABRA1 3149/4885GABRG2 4247/4885GABRB3 4371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.