Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.53 |
| ▸ | GABRP | O00591 | 3/20 | 0.53 |
| ▸ | GABRD | O14764 | 3/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.53 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.53 |
| ▸ | GABRE | P78334 | 3/20 | 0.53 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.53 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.53 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.53 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | IKBKB | O14920 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2391060 | 1.00 | GABRA1 (0.53) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL12590234 | 0.81 | CHUK (0.53) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL12590229 | 0.79 | ACHE (0.52) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL12396543 | 0.79 | MAPK14 (0.42) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL12590228 | 0.77 | GABRA1 (0.47) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL1849463 | 0.77 | MAPT (0.49) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL1458276 | 0.76 | CDK4 (0.59) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL30103963 | 0.76 | CDK4 (0.59) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2628321 | 0.75 | GABRP (0.49) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2628327 | 0.75 | KDM4E (0.55) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117843647-A | 5H-pyrimido [5,4-b ] indole derivative and preparation method thereof | 合肥工业大学 | 2024-04-09 | — | — | CN | claimed |
| EP-4633739-A1 | COMPOUNDS AND COMPOSITION FOR TARGETING TP53-Y220C MUTANTS | Flare Therapeutics, Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024129715-A1 | COMPOUNDS AND COMPOSITION FOR TARGETING TP53-Y220C MUTANTS | FLARE THERAPEUTICS INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| CN-117843647-A | 5H-pyrimido [5,4-b ] indole derivative and preparation method thereof | 合肥工业大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-117843647-A | 5H-pyrimido [5,4-b ] indole derivative and preparation method thereof | 合肥工业大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-117843647-A | 5H-pyrimido [5,4-b ] indole derivative and preparation method thereof | 合肥工业大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-116635383-A | Heterocyclic compound and organic light-emitting element comprising same | LT素材株式会社 | 2023-08-22 | — | — | CN | disclosed |
| CN-116113424-A | Fast vaccine platform | 赛托纳斯治疗公司 | 2023-05-12 | — | — | CN | disclosed |